Literaturangaben

Parodontitis als systemische Erkrankung

• Beck, J., et al.: Periodontal disease and cardiovascular disease. J. Periodontol, 67 (10): 1123–1137, 1996
• Derradjia, A., et al.: α-tocopherol decreases interleukin-1β and -6 and increases human β-defensin-1 and -2 secretion in human gingival fibroblasts stimulated with Porphyromonas gingivalis lipopolysaccharide. J Periodontal Res. 51(3): 295–303, 2016, doi: 10.1111/jre.12308. Epub 17.07.2015
• Gätke, D., Kocher, T.: Study of Health in Pomerania (SHIP) – eine Gesundheitsstudie in Ostdeutschland. Risikofaktoren für Parodontitis und Parodontitis als Risikofaktor für kardiovaskuläre Erkrankungen. Prophylaxe Dialog, 2/2007–1/2008: 7–8
• Howells, G.L.: Cytokine networks in destructive periodontal disease. Oral Diseases, 1(4): 266–270, 1995
• Jockel-Schneider, Y., et al.: Arterial stiffness and pulse wave reflection are increased in patients suffering from severe periodontitis. PLOS ONE 9(8): e103449. doi.org/10.1371/journal.pone.0103449
• Kocher, T., et al.: Parodontitis marginalis und kardiovaskuläre Erkrankungen. Dtsch Ärztebl 96 (42): A-2678/B-2283/C-2146, 1999
• Ngozi, N., et al.: Periodontal disease and incident cancer risk among postmenopausal women: results from the women's health initiative observational cohort. Cancer Epidemiology, Biomarkers & Prevention, 26, 8, 1255–1265, 2017, doi: 10.1158/1055-9965.EPI-17-0212
• Oral health in America: A Reports of the Surgeon General, 2000
• Paju , S., et al.: Porphyromonas gingivalis may interfere with conception in women. University of Helsinki, Journal of Oral Microbiology, 9: 1, 1330644, 2017, doi.org/10.1080/20002297.2017.1330644
• Pradhan-Palikhe, P., et al.: Elevated MMP-8 and decreased myeloperoxidase concentrations associate significantly with the risk for peripheral atherosclerosis disease and abdominal aortic aneurysm. Scand J Immunol. 72(2): 150–157, 2010, doi: 10.1111/j.1365-3083.2010.02418.x
• Scannapieco, F.A., et al.: Periodontal disease as a risk factor for adverse pregnancy outcomes. A systematic review. Ann Periodontol 8(1): 70–78, 2003

Nährstoffe & Ernährung bei Parodontitis

• Muniz, F.W.M.G., et al.: The impact of antioxidant agents complimentary to periodontal therapy on oxidative stress and periodontal outcomes: A systematic review. Archives of oral biology 60, 1203–1214, 2015
• Van der Velden, U.: Micronutritional approaches to periodontal therapy. J Clin Periodontol. 38, 11: 142–158, 2011, doi: 10.1111/j.1600-051X.2010.01663.x
• Wölber, J., Tennert, Ch: Fortbildung Parodontologie. Parodontitis und Ernährung. zm online vom 01.12.2017, www.zm-online.de/archiv/2017/23_24/zahnmedizin/parodontitis-und-ernaehrung/

Ballaststoffe

• Merchant, A.T., et al.: Whole-grain and fiber intakes and periodontitis risk in men. Am. J. Clin. Nutr. 83, 1395–1400, 2006
• Nielsen, S.J., et al.: Dietary fiber intake is inversely associated with periodontal disease among US adults. J. Nutr. 146, 2530–2536, 2016, doi:10.3945/jn.116.237065

Calcium / Magnesium

• Varela-López, A., et al.: A Systematic Review on the Implication of Minerals in the Onset, Severity and Treatment of Periodontal Disease. Molecules 21, 2016, doi:10.3390/molecules21091183

Coenzym Q10

• Folkers, K., Yamamura, Y., eds.: Biomedical and Clinical Aspects of Coenzyme Q. Vol 5. Elsevier, Amsterdam, 294–311, 1986
• Soni, S., et al.: Coenzyme Q10 and periodontal health: A review. International Journal of Oral and Maxillofacial Pathology, 3(2):21-26, 2012

Vitamin B12

• Zong, G., et al.: Serum vitamin B12 is inversely associated with periodontal progression and risk of tooth loss: a prospective cohort study. J. Clin. Periodontol. 43, 2–9, 2016, doi:10.1111/jcpe.12483

Vitamin D

• Uwitonze, A.M., et al.: Effects of vitamin D status on oral health. J Steroid Biochem Mol Biol. 175: 190–194, 2018, www.ncbi.nlm.nih.gov/pubmed/28161532

Vitamin C

• Li, X., et al.: Role of vitamin C in wound healing after dental implant surgery in patients treated with bone grafts and patients with chronic periodontitis. Clin Implant Dent Relat Res. 24.07.2018 [Epub ahead of print], doi: 10.1111/cid.12647
• Staudte, H., et al: Grapefruit consumption improves vitamin C status in periodontitis patients. Br Dent J 199, 213–217, discussion 210, 2005, doi:10.1038/sj.bdj.4812613
• Woelber, J.P., et al.: An oral health optimized diet can reduce gingival and periodontal inflammation in humans – a randomized controlled pilot study. BMC Oral Health 17, 28, 2016, doi:10.1186/s12903–016–0257–1

Vitamin E

• Singh, N., et al.: Vitamin E supplementation, superoxide dismutase status, and outcome of scaling and root planing in patients with chronic periodontitis: A randomized clinical trial. J of Periodontology, 85(2): 242–249, 2014, doi.org/10.1902/jop.2013.120727

Omega-3-Fettsäuren

• Chee, B., et al.: Omega-3 fatty acids as an adjunct for periodontal therapy-a review. Clin Oral Investig 20, 879–894, 2016, doi:10.1007/s00784–016–1750–2

Wirkung von Itis-Protect® bei Parodontitis

• Olbertz, H.-P.: Orthomolekulare Substitution bei Parodontitis und Regulationsstörungen – eine monozentrische Reproduzierbarkeitsstudie. Thesis zur Erlangung des Grades Master of Science am Interuniversitären Kolleg für Gesundheit und Entwicklung, Graz 2005
• Olbertz, H.-P., et al.: Adjuvante Behandlung refraktärer chronischer Parodontitis mittels Orthomolekularia – eine prospektive Pilotstudie aus der Praxis, Dentale Implantologie – DI 15, 1, 40–44, 2011

Mikrobiom

• Bosch, T.C.G.: Der Mensch als Holobiont – Mikroben als Schlüssel zu einem neuen Verständnis von Leben und Gesundheit (Natur und Wissen 1), 2018
• Kilian, M., et al.: The oral microbiome – an update for oral healthcare professionals. Br Dent J. 221(10): 657–666, 2016, doi: 10.1038/sj.bdj.2016.865
• Samboll, Th.: Kampf gegen Parodontitis. Transplantierte Mikroben sorgen für gesunde Mundflora. www.deutschlandfunk.de/kampf-gegen-parodontitis-transplantierte-mikroben-sorgen.676.de.html

aMMP-8 als Parodontitis-Marker

• Al-Majid, A., et al.: Review Article. Matrix metalloproteinase-8 as an inflammatory and prevention biomarker in periodontal and peri-implant diseases. 5: 1–27, 2018, doi: 10.1155/2018/7891323
• Reinhardt, R.A., et al.: Association of GCF biomarkers during periodontal maintenance with subsequent progressive periodontitis. Journal of Periodontology, 81, 2: 251–259, 2010
• Sorsa, T., et al.: Matrix metalloproteinases (MMPs) in oral diseases. Oral Dis 2004, 10: 311–318,
• Xu, L., et al.: Characteristics of collagenase-2 from gingival crevicular fluid and peri-implant sulcular fluid in periodontitis and peri-implantitis patients: pilot study. Acta Odontologica Scandinavica, 66, 4: 219–224, 2008